Progress begins with innovation

Long awaited, the fifth revised edition of The Diagnostic and Statistical Manual of Mental Disorders (DSM-V) will become the main reference for psychiatrists and neurologists upon its release in 2012. The primary focus of the new revision is to classify brain disorders according to their biological markers – endopheno types. The new approach assumes that a psychiatric diagnosis is made not only from behavior, but also from the knowledge of which brain system is impaired. Parameters of quantitative electroencephalogram (QEEG) and components of event-related potentials (ERPs) are considered as the most effective biological markers.

The renaissance is associated with the development of new methods of analysis and breakthrough discoveries pertaining to the neuronal mechanisms of EEG. The majority of the new methods (e.g. the decomposition of EEG and evoked responses into independent components, and LORETA - Low Resolution Electromagnetic Tomography) were initiated in laboratory settings only a few years ago. There is an urgent need however to introduce these new methods into clinical practice. Unfortunately, none of the existing normative data bases use the newly developed technologies.

This flaw of the current databases is resolved in a new database built up on the methodology developed in the Human Brain Institute (HBI) of the Russian Academy of Sciences and the Institute for Experimental Medicine of the Russian Medical Academy of Sciences. This methodology was awarded the USSR State Prize (the highest scientific award in the former Soviet Union) and is officially recognized as a unique discovery in the field of human physiology. The database is now used in many scientific centers abroad as well as in clinical practises in Europe and the USA.

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